Parvovirus B guidance, data and analysis
Parvovirus B19 is a single-stranded DNA virus belonging to the Parvoviridae family of viruses, which includes a number of animal parvoviruses such as the canine parvovirus and feline panleukopenia virus. Parvoviruses are species specific, and animal parvoviruses do not infect humans.
The most common symptom of parvovirus B19 is a facial rash, which spreads to the trunk and limbs, usually preceded by a non-specific flu-like illness. For most people, infection is mild and treatment is not required.
Infection is most common in children aged 6 to 10 years, but can occur at any age.
At least 50% to 70% of pregnant women are likely to already be immune to parvovirus B In women who are not immune, infection in the first 20 weeks of pregnancy can lead to serious adverse outcomes in the fetus: hydrops fetalis and intrauterine death. These consequences usually occur some 3 to 5 weeks after the onset of maternal infection, but can be later.
There is no vaccine available to prevent infection.
Diagnosis
The Immunisation and diagnosis unit (IDU) provides diagnostic and reference services for parvovirus B
Management
See the guidance for contr
Erythema infectiosum
Erythema infectiosum — extra information
InfectionsRashes
Author: Hon A/Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand, Updated September
Introduction
Causes
Demographics
Symptoms
Complications
Diagnosis
Treatment
What is erythema infectiosum?
Erythema infectiosum is a common childhood infection causing a slapped cheek appearance and a rash. It is also known as fifth disease and human erythrovirus infection.
What is the cause of erythema infectiosum?
Erythema infectiosum is caused by an erythrovirus, EVB19 or Parvovirus B It is a single-stranded DNA virus that targets red cells in the bone marrow. It spreads via respiratory droplets, and has an incubation period of 7–10 days.
Who gets erythema infectiosum?
Erythema infectiosum most commonly affects young children and often occurs in several members of the family or school class. Thirty percent of infected individuals have no symptoms. It can also affect adults that have not been previously exposed to the virus.
Fifth disease
Fifth disease
Fifth disease
See more images of erythema infectiosum
What are the symptoms of erythema infectiosum
Anemi hos immunsupprimerade och patienter med blodsjukdomar.
Infektion under graviditet kan ge upphov till spontanabort. Största risken är under andra tredjedelen av graviditeten. Totalt anses risken vara 5–10 % hos gravida med symtomatisk infektion.
Hydrops fetalis är ett syndrom med anemi, störd leverfunktion, myokardit, takykardi och ascites hos fostret och kan ha många orsaker, bl a parvovirus B Risken för denna komplikation vid parvovirusinfektion hos modern anges till 1–2 %. Ingen ökad risk finns för fostermissbildningar.
Immunitet mot parvovirus B19 kan testas genom IgG-antikroppar. Screening av gravida anses inte meningsfullt, men det är viktigt att ställa diagnos vid misstänkt primärinfektion, eftersom det kan föranleda extra ultraljudskontroller av fostret.
Vid hydrops fetalis kan det bli aktuellt med behandling i form av intrauterin blodtransfusion.
Sällsynt komplikation är Sock and Glove syndrome (PPGSS)-papulära utslag som ser ut som små blödningar (purpura) med tydlig distribution över händer och fötter och patienten har feber och lätt sänkt trombycytantal.
Frequently Asked Questions: Parvovirus B19 (Slapped cheek, syndrome, Fifth Disease)
What is parvovirus B19 (Parvovirus)?
Parvovirus B19 is a common childhood viral illness. It is a mild illness and can affect all age groups but is more common in children than adults. Approximately 60% of adults have been infected at some point and cannot be re-infected. In rare cases infection during pregnancy can be harmful to the developing baby. Parvovirus B19 only infects humans and cannot be picked up from animals. It spreads from person-to-person. Parvovirus B19 is not a notifiable disease in Ireland.
Human parvovirus B19 infection is also called:
- Slapped cheek syndrome
- Fifth disease
- Erythema infectiosum
What are the symptoms of parvovirus B19?
% of people infected with parvovirus B19 get no symptoms. If symptoms do occur they are usually mild and may include:
- fever
- runny nose
- headache
- rash on the face and/or body.
Symptoms can take between 4 to 20 days to appear after infection, but usually 13 to 18 days.
Symptoms vary depending on whether you get the infection as a child or an adult.
Children:
The red rash on the face called “slapped cheek” rash is the most
.
Anemi hos immunsupprimerade och patienter med blodsjukdomar.
Infektion under graviditet kan ge upphov till spontanabort. Största risken är under andra tredjedelen av graviditeten. Totalt anses risken vara 5–10 % hos gravida med symtomatisk infektion.
Hydrops fetalis är ett syndrom med anemi, störd leverfunktion, myokardit, takykardi och ascites hos fostret och kan ha många orsaker, bl a parvovirus B Risken för denna komplikation vid parvovirusinfektion hos modern anges till 1–2 %. Ingen ökad risk finns för fostermissbildningar.
Immunitet mot parvovirus B19 kan testas genom IgG-antikroppar. Screening av gravida anses inte meningsfullt, men det är viktigt att ställa diagnos vid misstänkt primärinfektion, eftersom det kan föranleda extra ultraljudskontroller av fostret.
Vid hydrops fetalis kan det bli aktuellt med behandling i form av intrauterin blodtransfusion.
Sällsynt komplikation är Sock and Glove syndrome (PPGSS)-papulära utslag som ser ut som små blödningar (purpura) med tydlig distribution över händer och fötter och patienten har feber och lätt sänkt trombycytantal.
Frequently Asked Questions: Parvovirus B19 (Slapped cheek, syndrome, Fifth Disease)
What is parvovirus B19 (Parvovirus)?
Parvovirus B19 is a common childhood viral illness. It is a mild illness and can affect all age groups but is more common in children than adults. Approximately 60% of adults have been infected at some point and cannot be re-infected. In rare cases infection during pregnancy can be harmful to the developing baby. Parvovirus B19 only infects humans and cannot be picked up from animals. It spreads from person-to-person. Parvovirus B19 is not a notifiable disease in Ireland.
Human parvovirus B19 infection is also called:
- Slapped cheek syndrome
- Fifth disease
- Erythema infectiosum
What are the symptoms of parvovirus B19?
% of people infected with parvovirus B19 get no symptoms. If symptoms do occur they are usually mild and may include:
- fever
- runny nose
- headache
- rash on the face and/or body.
Symptoms can take between 4 to 20 days to appear after infection, but usually 13 to 18 days.
Symptoms vary depending on whether you get the infection as a child or an adult.
Children:
The red rash on the face called “slapped cheek” rash is the most
.